Assignment of the bovine attractin (ATRN) gene to chromosome 13q21q22 by in situ hybridization.

Attractin (ATRN, mahogany) is a gene involved in the regulation of pigmentation, body weight regulation and formation of the central nervous system in mammals (Gunn et al., 2001; He et al., 2001). Moreover, a soluble form of attractin found in humans is implicated in monocyte spreading and T-cell clustering (Duke-Cohan et al., 1998). In mice Atrn was mapped to MMU2, 73.9 cM (www.informatics.jax.org). By EST database searching Tang et al., (2000) mapped ATRN to human chromosome 20p13. Bovine ATRN was mapped to chromosome 13 by linkage analysis (Edeal et al., 2000). Here we report the physical mapping of bovine ATRN to BTA 13q21→22 by FISH. Materials and methods